Tag Archive | Diseases
The D&D Compendium may be chock full of monsters, items, and powers, but one thing it still lacks is a list of the 4th edition diseases (Update: It now has diseases.). If you’ve ever tried to put a disease in your game, you know finding them is quite a task: they are scattered about in a handful of different source books and articles with no index in which to look them up… until now.
More Diseases: A List of 4th Edition Diseases From 3rd Party Sources
Following up on my Comprehensive List of Diseases in 4th Edition, the following is a compilation of many diseases appearing in 3rd party sources. They are listed here broken down first by level for easy reference and then, in a separate set of tables, by publisher, so you can quickly see what diseases are available in the books you have.
THIRD PARTY PUBLISHERS – DISEASES BY LEVEL
LEVEL
|
DISEASE
|
DESCRIPTION
|
SOURCE
|
Lvl 01
|
Chimney
|
A nuisance at most, sufferers exhibit a loud, dry cough, and breath that smells like soot.
|
Kobold Quarterly 12
(p.57) |
Lvl 02
|
Couplet (Curse)
|
Your curse compels the target to speak in rhyme, to your great amusement and their tongue-twisted dismay.
|
Hero’s Handbook: Eladrin
(p.36) |
Lvl 02
|
Hobbles
|
Victims of hobbles suffer from swelling of the extremities, tenderness of the feet, and joint pain. Walking becomes uncomfortable and running painful (if not impossible) as the disease progresses.
|
Monsterecology: Orcs
(p.29) |
Lvl 02
|
Tumbledown
|
Often spread when the target swims in or drinks tainted water, the disease causes severe vertigo and makes it impossible for the sufferer to stand.
|
|
Lvl 03
|
Dark Rot
|
Some say this disease was created in Morgau as a means to speed the living onto the land of dead. Dark Rot appears at random, so its contagion is still not fully understood.
|
|
Lvl 03
|
Iron Rot
|
Rusted metal of all sorts, from old sword blades to discarded nails, carries iron rot. The victim’s joints slowly stiffen until movement of any kind, even speech, is impossible…
|
|
Lvl 04
|
Night’s Delusions
|
This disease travels on the blades of weapons. At first, sufferers feel a sense of elation, but this gradually leads to dreamlike illusions.
|
|
Lvl 04
|
Skinpaper
|
The sufferer’s skin becomes dry and rigid, tearing open at the least scratch. The final stage causes the infected person to suffer horrible wounds when injured.
|
|
Lvl 05
|
Bloat Gloom
|
So named because the target’s face and limbs swell noticeably, the disease deadens pain from physical injuries and makes the sufferer oblivious to the severity of his wounds.
|
|
Lvl 05
|
Trasmute Emotions (Curse)
|
Your curse robs the target of all normal feelings. You choose to replace all of the target’s emotions with giddy joy and laughter, or deepest misery.
|
Hero’s Handbook: Eladrin
(p.36) |
Lvl 06
|
Blood Rotting Sickness
|
Any cut from centaur arrows taints the blood and leaves victims feverish and weak.
|
Kobold Quarterly 7
(p.44) |
Lvl 06
|
Bonewrack
|
Spread through insect bites, this disease causes horrible joint pain. A confounding illness, bonewrack seems to get worse just before the target recovers.
|
|
Lvl 06
|
The Fugue
|
Stale tomb air and fouled water transmit the fugue. Those afflicted report waking up in places or circumstances in which they have no memory of entering.
|
|
Lvl 07
|
Blue Ague
|
Carried on the foul vapors from sewers or through food, this disease befuddles the mind, causing the sufferer to act as if in a torpor.
|
|
Lvl 08
|
Angel Fire
|
This disease is so named because the sufferer’s flesh burns with radiant energy that only worsens in the presence of healing magic.
|
|
Lvl 08
|
Larval Infestation
|
||
Lvl 08
|
Sailor Fever
|
Often thought to be the reaction of a sailor who has lost his mind after too many days at sea, this disease spreads through flea and tick bites and manifests anywhere those vermin are plentiful.
|
|
Lvl 08
|
Searing Fever
|
The symptoms of searing sickness include fever, extreme headache, joint pain, and blindness.
|
Monsterecology: Orcs
(p.34) |
Lvl 09
|
Bleeding Blights
|
Thinned blood causes the victim to bleed profusely from even the slightest wound.
|
|
Lvl 09
|
Necrophage
|
||
Lvl 10
|
Fool’s Cap (Curse)
|
Your curse gives the target an ass’s head, matching external reality to essential truth.
|
Hero’s Handbook: Eladrin
(p.36) |
Lvl 11
|
Tremors
|
Contracted through addiction to Requiem, this disease is marked by sweating, vomiting, and un- controllable muscle spasms.
|
Kobold Quarterly 9
(p.57) |
Lvl 12
|
Bauble (Curse)
|
Your curse causes the target to prize the possession you des- ignate over all other things, an obsession that quickly grows into madness.
|
Hero’s Handbook: Eladrin
(p.35) |
Lvl 14
|
Feral Hunger (Curse)
|
Your curse causes the target to become revolted at the sight of ordinary food and crave grass, hay, or blood instead.
|
Hero’s Handbook: Eladrin
(p.36) |
Lvl 14
|
Fungal Infestation
|
This disease infects the target with a virulent strain of fungal growth. The fungus slowly poisons the target, and creates a severe, and potentially deadly allergy to sunlight within its host.
|
|
Lvl 15
|
Thew Blight
|
A particularly horrid disease, thew blight slowly liquefies muscle tissue until the victim is little more than immobile lump of wither flesh.
|
|
Lvl 16
|
Madness of the Wailing Wind
|
The insidious wind whistles in your ears, whispering blasphemous secrets impossible to ignore.
|
Kobold Quarterly 11
(p70) |
Lvl 16
|
Spetic Death
|
Rampant, flesh-eating bacteria devour the victim from the inside out.
|
|
Lvl 22
|
Gaes Curse
|
Azagar’s Book of Rituals
(p.11) |
|
Lvl 22
|
Skinchanger (Curse)
|
Your curse causes the target to spend half of each day as an ordinary animal with animal intelligence and instincts.
|
Hero’s Handbook: Eladrin
(p.36) |
Lvl 25
|
Cannibal Curse
|
You are overcome with a terrible desire to eat the flesh of your own kind… even if you have
|
SOURCE
|
DISEASE
|
LEVEL
|
DESCRIPTION
|
Azagar’s Book of Rituals
(p.11) |
Gaes Curse
|
Lvl 22
|
|
Fungal Infestation
|
Lvl 14
|
This disease infects the target with a virulent strain of fungal growth. The fungus slowly poisons the target, and creates a severe, and potentially deadly allergy to sunlight within its host.
|
|
(p.91)
|
Thew Blight
|
Lvl 15
|
A particularly horrid disease, thew blight slowly liquefies muscle tissue until the victim is little more than immobile lump of wither flesh.
|
(p.91)
|
Cannibal Curse
|
Lvl 25
|
You are overcome with a terrible desire to eat the flesh of your own kind… even if you have
|
Larval Infestation
|
Lvl 8
|
||
Bleeding Blights
|
Lvl 9
|
Thinned blood causes the victim to bleed profusely from even the slightest wound.
|
|
Septic Death
|
Lvl 16
|
Rampant, flesh-eating bacteria devour the victim from the inside out.
|
|
Necrophage
|
Lvl 9
|
||
Monsterecology: Orcs
(p.29) |
Hobbles
|
Lvl 2
|
Victims of hobbles suffer from swelling of the extremities, tenderness of the feet, and joint pain. Walking becomes uncomfortable and running painful (if not impossible) as the disease progresses.
|
(p.34)
|
Searing Fever
|
Lvl 8
|
The symptoms of searing sickness include fever, extreme headache, joint pain, and blindness.
|
Hero’s Handbook: Eladrin
(p.35) |
Bauble (Curse)
|
Lvl 12
|
Your curse causes the target to prize the possession you des- ignate over all other things, an obsession that quickly grows into madness.
|
(p.36)
|
Couplet (Curse)
|
Lvl 2
|
Your curse compels the target to speak in rhyme, to your great amusement and their tongue-twisted dismay.
|
(p.36)
|
Fool’s Cap (Curse)
|
Lvl 10
|
Your curse gives the target an ass’s head, matching external reality to essential truth.
|
(p.36)
|
Feral Hunger (Curse)
|
Lvl 14
|
Your curse causes the target to become revolted at the sight of ordinary food and crave grass, hay, or blood instead.
|
(p.36)
|
Trasmute Emotions (Curse)
|
Lvl 5
|
Your curse robs the target of all normal feelings. You choose to replace all of the target’s emotions with giddy joy and laughter, or deepest misery.
|
(p.36)
|
Skinchanger (Curse)
|
Lvl 22
|
Your curse causes the target to spend half of each day as an ordinary animal with animal intelligence and instincts.
|
SOURCE
|
DISEASE
|
LEVEL
|
DESCRIPTION
|
Kobold Quarterly 7
(p.44) |
Blood Rotting Sickness
|
Lvl 6
|
Any cut from centaur arrows taints the blood and leaves victims feverish and weak.
|
Kobold Quarterly 9
(p.57) |
Tremors
|
Lvl 11
|
Contracted through addiction to Requiem, this disease is marked by sweating, vomiting, and un- controllable muscle spasms.
|
Kobold Quarterly 11
(p70) |
Madness of the Wailing Wind
|
Lvl 16
|
The insidious wind whistles in your ears, whispering blasphemous secrets impossible to ignore.
|
Kobold Quarterly 12
(p.57) |
Chimney
|
Lvl 1
|
A nuisance at most, sufferers exhibit a loud, dry cough, and breath that smells like soot.
|
(p.57)
|
Tumbledown
|
Lvl 2
|
Often spread when the target swims in or drinks tainted water, the disease causes severe vertigo and makes it impossible for the sufferer to stand.
|
(p.57)
|
Dark Rot
|
Lvl 3
|
Some say this disease was created in Morgau as a means to speed the living onto the land of dead. Dark Rot appears at random, so its contagion is still not fully understood.
|
(p.57)
|
Skinpaper
|
Lvl 4
|
The sufferer’s skin becomes dry and rigid, tearing open at the least scratch. The final stage causes the infected person to suffer horrible wounds when injured.
|
(p.59)
|
Bloat Gloom
|
Lvl 5
|
So named because the target’s face and limbs swell noticeably, the disease deadens pain from physical injuries and makes the sufferer oblivious to the severity of his wounds.
|
(p.59)
|
Bonewrack
|
Lvl 6
|
Spread through insect bites, this disease causes horrible joint pain. A confounding illness, bonewrack seems to get worse just before the target recovers.
|
(p.59)
|
Blue Ague
|
Lvl 7
|
Carried on the foul vapors from sewers or through food, this disease befuddles the mind, causing the sufferer to act as if in a torpor.
|
(p.59)
|
Angel Fire
|
Lvl 8
|
This disease is so named because the sufferer’s flesh burns with radiant energy that only worsens in the presence of healing magic.
|
Iron Rot
|
Lvl 3
|
Rusted metal of all sorts, from old sword blades to discarded nails, carries iron rot. The victim’s joints slowly stiffen until movement of any kind, even speech, is impossible…
|
|
Night’s Delusions
|
Lvl 4
|
This disease travels on the blades of weapons. At first, sufferers feel a sense of elation, but this gradually leads to dreamlike illusions.
|
|
The Fugue
|
Lvl 6
|
Stale tomb air and fouled water transmit the fugue. Those afflicted report waking up in places or circumstances in which they have no memory of entering.
|
|
Sailor Fever
|
Lvl 8
|
Often thought to be the reaction of a sailor who has lost his mind after too many days at sea, this disease spreads through flea and tick bites and manifests anywhere those vermin are plentiful.
|
A Comprehensive List of Diseases in 4th Edition

Rot Grub Infestation
Below is a compilation of most (if not all) of the 4th edition diseases to appear in any official source book, adventure, or DDI article to date. They are listed here broken down first by level for easy reference and then, in a separate set of tables, by source book, so you can quickly see what diseases are available in the books you have.
In a later post I will provide an index of some of the diseases created in 3rd party materials.
WIZARDS OF THE COAST – DISEASES BY LEVEL
LEVEL
|
DISEASE
|
DESCRIPTION
|
SOURCE
|
Lvl 02
|
Skinrot
|
||
Lvl 03
|
Filth Fever
|
Dungeon 156 (p.33, 42),
Dungeon 150 (p.96), Monster Manual (p.180, 211, 219)
|
|
Lvl 04
|
Shakes
|
This disease causes involuntary twitches and tremors that grow progressively worse.
|
Dungeon Master’s Guide (p.50)
|
Lvl 06
|
Moontusk Fever
|
Monster Manual 2 (p.158)
|
|
Lvl 06
|
Slavering Canker
|
Monster Manual 2 (p.126)
|
|
Lvl 06
|
Verdant Whispers
|
Spread by touch, verdant whispers causes victims to enter a delirious state.
|
Dragon 364 (p.72)
|
Lvl 08
|
Lockjaw
|
Dungeon 178 (p.76)
|
|
Lvl 08
|
Moon Fever
|
Dungeon 156 (p.53)
|
|
Lvl 08
|
Moon Frenzy
|
H3: Pyramid of Shadows (p.23), Monster Manual (p.181)
|
|
Lvl 08
|
Mummy Rot (Mummy Guardian)
|
Monster Manual (p.192)
|
|
Lvl 08
|
Rusty Paralysis
|
This disease affects those cut by rusty metal. The victim gets slowly weaker, and in the final stages the victim becomes paralyzed.
|
Dragon 376 (p.32)
|
Lvl 08+
|
Mummy Rot
|
This disease, delivered by the attack of a mummy, fills the lungs of its victims with dust, making it progressively harder for them to breathe.
|
Dungeon Master’s Guide (p.49)
|
Lvl 09
|
Blinding Sickness
|
Often spread in tainted water, blinding sickness leaves its victims sightless.
|
Dungeon Master’s Guide (p.49)
|
Lvl 10
|
Festering Doom
|
Black sores appear on the skin, oozing black filth and vital fluids when exposed to healing magic.
|
Dungeon 161 (p.112)
|
Lvl 11
|
Cemetery Rot
|
||
Lvl 11
|
Halruaan Consumption
|
Those who contract this malady are subject to sudden weight loss, vomiting, and finally disintegration.
|
Eberron Campaign Guide (p.136)
|
Lvl 11
|
Moon Rage
|
Monster Manual 2 (p.159)
|
|
Lvl 11
|
Mournland Affliction
|
Afflicted by the Mournland, a victim of this disease acts as one without hope, sallow, wide-eyed, and despairing.
|
Eberron Campaign Guide (p.93)
|
Lvl 11
|
Soul Rot
|
Manual of the Planes (p.52)
|
|
Lvl 11
|
Worms of Kyuss
|
||
Lvl 12
|
Cackle Fever
|
The symptoms of cackle fever include high fever, disorientation, and frequent bouts of hideous laughter.
|
Dungeon Master’s Guide (p.49)
|
Lvl 12
|
Twisted Domination
|
Dungeon 157 (p.64)
|
|
Lvl 13
|
Brain Fluke
|
This minuscule, wormlike parasite concludes its adult life in a victim’s brain.
|
Forgotten Realms Campaign Guide (p.103)
|
Lvl 13
|
Greater Moon Frenzy
|
Monster Manual 2 (p.160)
|
|
Lvl 13
|
Mummy Rot (Mummy Lord)
|
Monster Manual (p.192)
|
|
Lvl 13
|
Tear Transformation
|
Dungeon 162 (p.79)
|
|
Lvl 14
|
Filth Plague
|
Infused with the toxic filth of the Demon Wastes, this disease turns the target’s internal organs to a bloody froth.
|
Dungeon 177 (p.20), Eberron Campaign Guide (p.121)
|
Lvl 16
|
Chaos Phage
|
||
Lvl 16
|
Mindfire
|
In the initial stages, victims of mindfire complain of burning pain in the head. Later, they sink into stupor.
|
Dungeon Master’s Guide (p.50)
|
Lvl 17
|
Mummy Rot
|
||
Lvl 20
|
Mind Seed
|
An implanted quori thought slowly takes root and grows until the victim is completely under its control.
|
Eberron Campaign Guide (p.190)
|
Lvl 21
|
Hellfever
|
Those who suffer from hellfever complain of alternating sensations of searing fire and freezing cold.
|
Dungeon Master’s Guide (p.50)
|
Lvl 21
|
Mummy Rot
|
Draconomicon: Metallic Dragons (p.142)
|
|
Lvl 21
|
Mummy Rot (Giant Mummy)
|
Monster Manual (p.192)
|
|
Lvl 23
|
Slimy Doom
|
Abyssal parasites devour the internal organs of the victims, turning them into quivering slime.
|
Dungeon Master’s Guide (p.50)
|
Lvl 26
|
Silvery Sleep
|
||
Variable
|
Pact Broken Curse
|
||
Character Level
|
Sun Sickness
|
Dark Sun Campaign Setting (p.199)
|
WIZARDS OF THE COAST – DISEASES BY BOOK
SOURCE BOOKS
SOURCE BOOKS
SOURCE
|
DISEASE
|
LEVEL
|
DESCRIPTION
|
Dark Sun Campaign Setting
(p.199) |
Sun Sickness
|
Character Level
|
The sun’s punishing rays leech vitality from your body.
|
Draconomicon: Metallic Dragons (p.142)
|
Mummy Rot
|
Lvl 21
|
|
Dungeon Master’s Guide
(p.49) |
Mummy Rot
|
Lvl 8+
|
This disease, delivered by the attack of a mummy, fills the lungs of its victims with dust, making it progressively harder for them to breathe.
|
(p.49)
|
Blinding Sickness
|
Lvl 9
|
Often spread in tainted water, blinding sickness leaves its victims sightless.
|
(p.49)
|
Cackle Fever
|
Lvl 12
|
The symptoms of cackle fever include high fever, disorientation, and frequent bouts of hideous laughter.
|
(p.50)
|
Shakes
|
Lvl 4
|
This disease causes involuntary twitches and tremors that grow progressively worse.
|
(p.50)
|
Mindfire
|
Lvl 16
|
In the initial stages, victims of mindfire complain of burning pain in the head. Later, they sink into stupor.
|
(p.50)
|
Hellfever
|
Lvl 21
|
Those who suffer from hellfever complain of alternating sensations of searing fire and freezing cold.
|
(p.50)
|
Slimy Doom
|
Lvl 23
|
Abyssal parasites devour the internal organs of the victims, turning them into quivering slime.
|
Eberron Campaign Guide
(p.93) |
Mournland Affliction
|
Lvl 11
|
Afflicted by the Mournland, a victim of this disease acts as one without hope, sallow, wide-eyed, and despairing.
|
(p.121)
|
Filth Plague
|
Lvl 14
|
Infused with the toxic filth of the Demon Wastes, this disease turns the targets internal organs into a bloody froth.
|
(p.190)
|
Mind Seed
|
Lvl 20
|
An implanted quori thought slowly takes root and grows until the victim is completely under its control.
|
Mummy Rot
|
Lvl 17
|
||
(p.123)
|
Silvery Sleep
|
Lvl 26
|
|
(p.180)
|
Skinrot
|
Lvl 2
|
|
(p.186)
|
Cemetery Rot
|
Lvl 11
|
|
(p.218)
|
Worms of Kyuss
|
Lvl 11
|
|
Monster Manual
(p.180, 211, 219) |
Filth Fever
|
Lvl 3
|
|
(p.181)
|
Moon Frenzy
|
Lvl 8
|
|
(p.192)
|
Mummy Rot (Mummy Guardian)
|
Lvl 8
|
|
(p.192)
|
Mummy Rot (Mummy Lord)
|
Lvl 13
|
|
(p.192)
|
Mummy Rot (Giant Mummy)
|
Lvl 21
|
|
(p.239)
|
Chaos Phage
|
Lvl 16
|
|
Manual of the Planes
(p.52) |
Soul Rot
|
Lvl 11
|
|
Monster Manual 2
(p.126) |
Slavering Canker
|
Lvl 6
|
|
(p.158)
|
Moontusk Fever
|
Lvl 6
|
|
(p.159)
|
Moon Rage
|
Lvl 11
|
|
(p.160)
|
Greater Moon Frenzy
|
Lvl 13
|
|
Pact Broken Curse
|
Variable
|
||
(p.103)
|
Brain Fluke
|
Lvl 13
|
This minuscule, wormlike parasite concludes its adult life in a victim’s brain.
|
(p.103)
|
Halruaan Consumption
|
Lvl 11
|
Those who contract this malady are subject to sudden weight loss, vomiting, and finally disintegration.
|
ADVENTURES
SOURCE
|
DISEASE
|
LEVEL
|
DESCRIPTION
|
H3: Pyramid of Shadows
(p.23) |
Moon Frenzy
|
Lvl 8
|
DRAGON MAGAZINE (up to 388)
SOURCE
|
DISEASE
|
LEVEL
|
DESCRIPTION
|
Dragon 364
(p.72) |
Verdant Whispers
|
Lvl 6
|
Spread by touch, verdant whispers causes victims to enter a delirious state.
|
Dragon 376
(p.32) |
Rusty Paralysis
|
Lvl 8
|
This disease affects those cut by rusty metal. The victim gets slowly weaker, and in the final stages the victim becomes paralyzed.
|
DRAGON MAGAZINE (up to 179)
SOURCE
|
DISEASE
|
LEVEL
|
DESCRIPTION
|
Dungeon 156
(p.33, 42) |
Filth Fever
|
Lvl 3
|
|
(p.53)
|
Moon Fever
|
Lvl 8
|
|
Dungeon 157
(p.64) |
Twisted Domination
|
Lvl 12
|
|
Dungeon 158
(p.96) |
Filth Fever
|
Lvl 3
|
|
Dungeon 161
(p.112) |
Festering Doom
|
Lvl 10
|
Black sores appear on the skin, oozing black filth and vital fluids when exposed to healing magic.
|
Dungeon 162
(p.15, 17, 20, 25) |
Chaos Phage
|
Lvl 16
|
|
(p.79)
|
Tear Transformation
|
Lvl 13
|
|
Dungeon 177
(p.20) |
Filth Plague
|
Lvl 14
|
Infused with the toxic filth of the Demon Wastes, this disease turns the target’s internal organs to a bloody froth.
|
Dungeon 178
(p.76) |
Lockjaw
|
Lvl 8
|
|
Chaos Phage
|
Lvl 16
|