A Comprehensive List of Diseases in 4th Edition

Rot Grub Infestation

The D&D Compendium may be chock full of monsters, items, and powers, but one thing it still lacks is a list of the 4th edition diseases (Update: It now has diseases.). If you’ve ever tried to put a disease in your game, you know finding them is quite a task: they are scattered about in a handful of different source books and articles with no index in which to look them up… until now.

Below is a compilation of most (if not all) of the 4th edition diseases to appear in any official source book, adventure, or DDI article to date. They are listed here broken down first by level for easy reference and then, in a separate set of tables, by source book, so you can quickly see what diseases are available in the books you have.

In a later post I will provide an index of some of the diseases created in 3rd party materials.


WIZARDS OF THE COAST – DISEASES BY LEVEL
LEVEL
DISEASE
DESCRIPTION
SOURCE
Lvl 02
Skinrot
Lvl 03
Filth Fever
Dungeon 156 (p.33, 42),
Dungeon 150 (p.96), Monster Manual (p.180, 211, 219)
Lvl 04
Shakes
This disease causes involuntary twitches and tremors that grow progressively worse.
Lvl 06
Moontusk Fever
Lvl 06
Slavering Canker
Lvl 06
Verdant Whispers
Spread by touch, verdant whispers causes victims to enter a delirious state.
Dragon 364 (p.72)
Lvl 08
Lockjaw
Lvl 08
Moon Fever
Lvl 08
Moon Frenzy
Lvl 08
Mummy Rot (Mummy Guardian)
Lvl 08
Rusty Paralysis
This disease affects those cut by rusty metal. The victim gets slowly weaker, and in the final stages the victim becomes paralyzed.
Dragon 376 (p.32)
Lvl 08+
Mummy Rot
This disease, delivered by the attack of a mummy, fills the lungs of its victims with dust, making it progressively harder for them to breathe.
Lvl 09
Blinding Sickness
Often spread in tainted water, blinding sickness leaves its victims sightless.
Lvl 10
Festering Doom
Black sores appear on the skin, oozing black filth and vital fluids when exposed to healing magic.
Dungeon 161 (p.112)
Lvl 11
Cemetery Rot
Lvl 11
Halruaan Consumption
Those who contract this malady are subject to sudden weight loss, vomiting, and finally disintegration.
Lvl 11
Moon Rage
Lvl 11
Mournland Affliction
Afflicted by the Mournland, a victim of this disease acts as one without hope, sallow, wide-eyed, and despairing.
Lvl 11
Soul Rot
Lvl 11
Worms of Kyuss
Lvl 12
Cackle Fever
The symptoms of cackle fever include high fever, disorientation, and frequent bouts of hideous laughter.
Lvl 12
Twisted Domination
Lvl 13
Brain Fluke
This minuscule, wormlike parasite concludes its adult life in a victim’s brain.
Lvl 13
Greater Moon Frenzy
Lvl 13
Mummy Rot (Mummy Lord)
Lvl 13
Tear Transformation
Lvl 14
Filth Plague
Infused with the toxic filth of the Demon Wastes, this disease turns the target’s internal organs to a bloody froth.
Lvl 16
Chaos Phage
Dungeon 179 (p.12, 17), Monster Manual (p239), Dungeon 162 (p.15, 17, 20, 25)
Lvl 16
Mindfire
In the initial stages, victims of mindfire complain of burning pain in the head. Later, they sink into stupor.
Lvl 17
Mummy Rot
Lvl 20
Mind Seed
An implanted quori thought slowly takes root and grows until the victim is completely under its control.
Lvl 21
Hellfever
Those who suffer from hellfever complain of alternating sensations of searing fire and freezing cold.
Lvl 21
Mummy Rot
Lvl 21
Mummy Rot (Giant Mummy)
Lvl 23
Slimy Doom
Abyssal parasites devour the internal organs of the victims, turning them into quivering slime.
Lvl 26
Silvery Sleep
Variable
Pact Broken Curse
Character Level
Sun Sickness
WIZARDS OF THE COAST – DISEASES BY BOOK
SOURCE BOOKS
SOURCE
DISEASE
LEVEL
DESCRIPTION
Sun Sickness
Character Level
The sun’s punishing rays leech vitality from your body.
Mummy Rot
Lvl 21
Mummy Rot
Lvl 8+
This disease, delivered by the attack of a mummy, fills the lungs of its victims with dust, making it progressively harder for them to breathe.
(p.49)
Blinding Sickness
Lvl 9
Often spread in tainted water, blinding sickness leaves its victims sightless.
(p.49)
Cackle Fever
Lvl 12
The symptoms of cackle fever include high fever, disorientation, and frequent bouts of hideous laughter.
(p.50)
Shakes
Lvl 4
This disease causes involuntary twitches and tremors that grow progressively worse.
(p.50)
Mindfire
Lvl 16
In the initial stages, victims of mindfire complain of burning pain in the head. Later, they sink into stupor.
(p.50)
Hellfever
Lvl 21
Those who suffer from hellfever complain of alternating sensations of searing fire and freezing cold.
(p.50)
Slimy Doom
Lvl 23
Abyssal parasites devour the internal organs of the victims, turning them into quivering slime.
Mournland Affliction
Lvl 11
Afflicted by the Mournland, a victim of this disease acts as one without hope, sallow, wide-eyed, and despairing.
(p.121)
Filth Plague
Lvl 14
Infused with the toxic filth of the Demon Wastes, this disease turns the targets internal organs into a bloody froth.
(p.190)
Mind Seed
Lvl 20
An implanted quori thought slowly takes root and grows until the victim is completely under its control.
Mummy Rot
Lvl 17
(p.123)
Silvery Sleep
Lvl 26
(p.180)
Skinrot
Lvl 2
(p.186)
Cemetery Rot
Lvl 11
(p.218)
Worms of Kyuss
Lvl 11
Monster Manual
(p.180, 211, 219)
Filth Fever
Lvl 3
(p.181)
Moon Frenzy
Lvl 8
(p.192)
Mummy Rot (Mummy Guardian)
Lvl 8
(p.192)
Mummy Rot (Mummy Lord)
Lvl 13
(p.192)
Mummy Rot (Giant Mummy)
Lvl 21
(p.239)
Chaos Phage
Lvl 16
Soul Rot
Lvl 11
Slavering Canker
Lvl 6
(p.158)
Moontusk Fever
Lvl 6
(p.159)
Moon Rage
Lvl 11
(p.160)
Greater Moon Frenzy
Lvl 13
Pact Broken Curse
Variable
(p.103)
Brain Fluke
Lvl 13
This minuscule, wormlike parasite concludes its adult life in a victim’s brain.
(p.103)
Halruaan Consumption
Lvl 11
Those who contract this malady are subject to sudden weight loss, vomiting, and finally disintegration.
ADVENTURES
SOURCE
DISEASE
LEVEL
DESCRIPTION
Moon Frenzy
Lvl 8
DRAGON MAGAZINE (up to 388)
SOURCE
DISEASE
LEVEL
DESCRIPTION
Verdant Whispers
Lvl 6
Spread by touch, verdant whispers causes victims to enter a delirious state.
Rusty Paralysis
Lvl 8
This disease affects those cut by rusty metal. The victim gets slowly weaker, and in the final stages the victim becomes paralyzed.
DRAGON MAGAZINE (up to 179)
SOURCE
DISEASE
LEVEL
DESCRIPTION
Dungeon 156
(p.33, 42)
Filth Fever
Lvl 3
(p.53)
Moon Fever
Lvl 8
Twisted Domination
Lvl 12
Filth Fever
Lvl 3
Festering Doom
Lvl 10
Black sores appear on the skin, oozing black filth and vital fluids when exposed to healing magic.
Dungeon 162
(p.15, 17, 20, 25)
Chaos Phage
Lvl 16
(p.79)
Tear Transformation
Lvl 13
Filth Plague
Lvl 14
Infused with the toxic filth of the Demon Wastes, this disease turns the target’s internal organs to a bloody froth.
Lockjaw
Lvl 8
Dungeon 179
(p.12, 17)
Chaos Phage
Lvl 16
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2 responses to “A Comprehensive List of Diseases in 4th Edition”

  1. Anonymous says :

    wow

    exactly what i was looking for!

    thanks alot

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